Assay
Age
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Immunohistochemistry (section)
18.5 DPC
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Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) (Synonyms: Slc25a7) | |
Results | Reference |
1 | J:158709 Gupta RK, Arany Z, Seale P, Mepani RJ, Ye L, Conroe HM, Roby YA, Kulaga H, Reed RR, Spiegelman BM, Transcriptional control of preadipocyte determination by Zfp423. Nature. 2010 Mar 25;464(7288):619-23 |
1* | J:314181 Holzman MA, Ryckman A, Finkelstein TM, Landry-Truchon K, Schindler KA, Bergmann JM, Jeannotte L, Mansfield JH, HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303 |
1 | J:273135 Jang Y, Broun A, Wang C, Park YK, Zhuang L, Lee JE, Froimchuk E, Liu C, Ge K, H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development. Nucleic Acids Res. 2019 Jan 25;47(2):607-620 |
1* | J:295426 Lee JE, Cho YW, Deng CX, Ge K, MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPbeta and C/EBPdelta. Mol Cell Biol. 2020 Aug 14;40(17) |
1* | J:254909 Lee JE, Park YK, Park S, Jang Y, Waring N, Dey A, Ozato K, Lai B, Peng W, Ge K, Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis. Nat Commun. 2017 Dec 20;8(1):2217 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:220963 Nosavanh L, Yu DH, Jaehnig EJ, Tong Q, Shen L, Chen MH, Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5069-74 |
1 | J:333724 Park EJ, Kim HS, Lee DH, Kim SM, Yoon JS, Lee JM, Im SJ, Lee H, Lee MW, Lee CW, Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation. Nat Commun. 2023 Feb 25;14(1):1097 |
1 | J:303562 Park YK, Lee JE, Yan Z, McKernan K, O'Haren T, Wang W, Peng W, Ge K, Interplay of BAF and MLL4 promotes cell type-specific enhancer activation. Nat Commun. 2021 Mar 12;12(1):1630 |
1 | J:244281 Park YK, Wang L, Giampietro A, Lai B, Lee JE, Ge K, Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor gamma in Adipogenesis. Mol Cell Biol. 2017 Jan 15;37(2) |
1 | J:327433 Song Z, Xiaoli AM, Li Y, Siqin G, Wu T, Strich R, Pessin JE, Yang F, The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation. Mol Metab. 2022 Jul 19;64:101548 |
1 | J:168191 Yadav N, Cheng D, Richard S, Morel M, Iyer VR, Aldaz CM, Bedford MT, CARM1 promotes adipocyte differentiation by coactivating PPARgamma. EMBO Rep. 2008 Feb;9(2):193-8 |
1* | J:228546 Zhou H, Wan B, Grubisic I, Kaplan T, Tjian R, TAF7L modulates brown adipose tissue formation. Elife. 2014;3 |
1 | J:262992 Zhuang L, Jang Y, Park YK, Lee JE, Jain S, Froimchuk E, Broun A, Liu C, Gavrilova O, Ge K, Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function. Nat Commun. 2018 May 4;9(1):1796 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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